Search Results - Pharmaceutical

33 Results Sort By:

Method for Improved Production of Terpenoids Using Co-Engineered Lipid Droplets and Anchoring of Terpene Biosynthetic Enzymes on Their Surface

Executive SummaryThis technology addresses one of the main hurdles of plant production and extraction of terpenoids by capturing desired terpenes in lipid droplets in plant cells. The lipid droplets are readily extracted using standard processes used in the vegetable oil and biodiesel industries, and the high-value terpenes can be easily separated...
Published: 5/28/2019   |   Inventor(s): Bjoern Hamberger, Radin Sadre, Christoph Benning, Jacob Bibik
Keywords(s):   Category(s): Agriculture, Chemicals, Biotechnology, Pharmaceutical

Method for Production of Novel Diterpene Scaffolds

Executive SummaryMany insecticides currently in use are problematic due to persistence in the environment and off target effects including accumulation in apex predator species. Therefore effective crop-protecting agents that are naturally sourced and that overcome some of these side effects are under increasing demand. This technology identifies biosynthetic...
Published: 5/28/2019   |   Inventor(s): Bjoern Hamberger, Sean Johnson, Wajid Bhat
Keywords(s):   Category(s): Agriculture, Chemicals, Biotechnology, Pharmaceutical

020009: Compositions and Methods for Epizootic Catarrhal Enteritis (ECE) Therapeutics and Diagnostics in Ferrets

In 1999, a coronavirus was identified as the cause of Epizootic Catarrhal Enteritis (ECE) in ferrets, a highly contagious diarrheal disease for which there are no effective diagnostics, therapeutics, or preventatives. This disease costs ferret breeders and owners millions of dollars a year in health care costs and lost revenue. In 1996, approximately...
Published: 11/27/2018   |   Inventor(s): Roger Maes, Matti Kiupel, Annabel Wise
Keywords(s): Coronavirus, Diagnosis, Ferret, Prevention, Screening, Treatment, Vaccine Category(s): Biotechnology, Pharmaceutical, Animal/Veterinary

Improving Pharmacokinetics and Efficacy of DFMO

Executive SummaryFor many years, the drug difluoromethylornithine (DFMO) has been shown to display chemopreventive and therapeutic properties with recent successes in the treatment of patients with high-risk neuroblastoma (NB) and colorectal cancer. In a non-cancer setting, this FDA-approved drug cures 95% of patients with West African sleeping sickness...
Published: 9/17/2018   |   Inventor(s): Andre Bachmann, Thomas Dowling
Keywords(s):   Category(s): Medical, Pharmaceutical

Novel MmpL3 Inhibitor as a Treatment of Mycobacterium Tuberculosis

Executive SummaryMycobacterium Tuberculosis (Mtb) is the pathogen responsible for Tuberculosis. Standard TB treatments typically require four different drugs and a duration of six to nine months of treatment; however, there is still an evolution of drug-resistant Mtb. With not only Tuberculosis, but drug-resistant Tuberculosis causing upwards of 1.5...
Published: 6/4/2018   |   Inventor(s): Robert Abramovitch, Huiqing Zheng
Keywords(s):   Category(s): Medical, Biotechnology, Pharmaceutical

Improved Technology for Mannitol Production

Executive SummaryIndustrialized production of mannitol for use as a food sweetener and various pharmaceutical applications is currently achieved by hydrogenation of a fructose/glucose syrup at high pressures and temperatures. The reaction produces a mixture of mannitol and sorbitol that is both inefficient (70% sorbitol as end-product) and requires...
Published: 5/31/2018   |   Inventor(s): Claire Vieille, Seung Hoon Song, J. Gregory Zeikus
Keywords(s):   Category(s): Chemicals, Biotechnology, Pharmaceutical

Novel Chemical Inhibitors of Mycobacterium Tuberculosis Targeting the DosRST Pathway – Tuberculosis Treatment

Executive SummaryTuberculosis (TB) is a potentially fatal infectious disease caused by the bacterium, Mycobacterium tuberculosis (Mtb). According to the Centers for Disease Control and Prevention (CDC), TB is one of the world’s deadliest diseases and responsible for upwards of 1.5 million deaths annually. TB is also a leading killer of HIV-infected...
Published: 5/24/2018   |   Inventor(s): Robert Abramovitch, Edmund Ellsworth
Keywords(s):   Category(s): Medical, Biotechnology, Pharmaceutical

Mobile Phone App for Real Time Pill Recognition

Executive SummaryThe ability to quickly and reliably be able to identify both prescription and non-prescription medications is not only important for a patient and his caretaker, but also important for pharmacists, nurses, and law enforcement agents. Despite unique FDA-approved identifiers for each pill, distinguishing the differences can be difficult...
Published: 4/18/2018   |   Inventor(s): Mi Zhang, Kai Cao, Xiao Zeng
Keywords(s):   Category(s): Medical, Computer Software, Pharmaceutical

Novel Compounds to Treat Canine Histiocytic Sarcomas and Other Malignancies

Executive SummaryHistiocytic sarcomas are very aggressive and invasive tumors that occur with high incidence in Bernese Mountain dogs, Rottweilers, Flat Coated Retrievers, and Golden Retrievers. The prognosis of histiocytic sarcomas is poor with median survival time of a few weeks to a few months. The currently available clinical treatments, including...
Published: 8/10/2017   |   Inventor(s): Vilma Yuzbasiyan-Gurkan, Jetze Tepe
Keywords(s):   Category(s): Medical, Animal/Veterinary, Pharmaceutical

Chemical Treatment for Osteoporosis

Executive SummaryCurrently available therapeutics for osteoporosis have the potential to produce severe negative side effects or are required to be administered via injection. Researchers at Michigan State University have developed a new therapeutic that overcomes these challenges.Description of TechnologyThis novel MSU technology uses high molecular...
Published: 6/28/2017   |   Inventor(s): Laura Mccabe, Rifat Pamukcu
Keywords(s):   Category(s): Biotechnology, Pharmaceutical
1 2 3 4