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Search Results - medical
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Stretchable Bioelectronic Interface for Biopotential Recording
Executive Summary Flexible electronics are materials that are often soft and bendable which allow them to conform to various surfaces. One application for these is in the bio
medical
field where flexible electrodes are used to measure electrical signals such as an electrocardiogram (ECG), electroencephalogram (EEG), or electromyography (EMG). However,...
Published: 11/15/2023
|
Inventor(s):
Jinxing Li
,
Vittorio Mottini
Keywords(s):
Category(s):
Medical
,
Devices
,
Advanced Materials
Biocatalysis of Bioactive Taxanes
Executive Summary Chemotherapy drugs are critical for effective patient cancer care. Unfortunately, the pharmaceutical industry has encountered several instances where it has not been able to supply sufficient quantities of important chemotherapy drugs due to manufacturing problems. Michigan State University researchers have discovered a novel, faster...
Published: 10/2/2023
|
Inventor(s):
Kevin Walker
Keywords(s):
Category(s):
Medical
,
Pharmaceutical
Polyethylene Implants with Controlled Immune Response
Executive Summary Polyethylene is commonly used as a material for
medical
implants such as total joint replacements. Unfortunately, polyethylene wear particles can promote adverse host immune responses in patients, which may require secondary revision surgery. MSU researchers have recently discovered that metabolic reprogramming and altered bioenergetics...
Published: 8/16/2023
|
Inventor(s):
Christopher Contag
,
Stuart Goodman
,
Chima Maduka
Keywords(s):
Category(s):
Medical
Rapid Point of Care Detection of Tuberculosis
Executive Summary Tuberculosis (TB) remains one of the major causes of death from a single infectious agent worldwide, affecting both humans and livestock. Pulmonary TB can be currently diagnosed by various methods including chest radiography, sputum smear microscopy, nucleic acid amplification and cultivation of Mycobacterium tuberculosis (Mtb). However,...
Published: 2/17/2023
|
Inventor(s):
Evangelyn Alocilja
Keywords(s):
Category(s):
Medical
,
Biotechnology
,
Veterinary
Synthetic Implants with Controlled Immune Response
Executive Summary Polymers such as polylactic acid (PLA) are commonly used as bioabsorbable materials for implants. Unfortunately, degradation products from these often promote adverse host immune responses in patients, which may require a secondary
medical
intervention such as surgery to remove the implant. To attempt to counter this, some...
Published: 6/12/2023
|
Inventor(s):
Chima Maduka
,
Christopher Contag
Keywords(s):
Category(s):
Medical
Bioluminescent Dopamine and Glutamate Sensors
Executive Summary Genetically encoded optical sensors and advancements in microscopy have revolutionized the scientific toolbox used for answering complex biological questions especially in terms of studying brain activity. However, there remains a need to develop new tools for reporting neuronal activity in vivo within deeper structures. MSU...
Published: 2/17/2023
|
Inventor(s):
Eric Petersen
Keywords(s):
Category(s):
Medical
,
Biotechnology
Extracellular Vesicle Library for Drug Screening
Executive Summary The body’s natural transporter, Extracellular vesicles (EVs), have gained recent attention for their potential as targeted drug delivery vehicles with low immunogenic response. Properly designing the surface allows EVs to deliver therapeutic payloads (protein, RNA, nanoparticle, small molecule, etc.) to a target organ....
Published: 10/16/2023
|
Inventor(s):
Christopher Contag
,
Masako Harada
Keywords(s):
Category(s):
Medical
,
Biotechnology
,
Pharmaceutical
Mechanistic Basis of Pyrethrum Repellency Against Mosquitoes
High-Throughput Screening Platform for Identification of Insect Repellents Executive Summary: High-throughput screening platform identifies repellent compounds that activate specific insect odor receptors. This platform can identify pyrethrins and pyrethroids to combine with odorant-mediated repellents to enhance overall repellant activity....
Published: 2/17/2023
|
Inventor(s):
Ke Dong
,
Feng Liu
,
Qiang Wang
,
Peng Xu
,
Felipe Andreazza
,
Wilson Valbon
Keywords(s):
Category(s):
Medical
,
Chemicals
,
Veterinary
Gold Nanoparticle Biosensors
Executive Summary Harmful microbes are present in a variety of sources including water, food, plants, and through human-to-human transmission. The ability to detect them rapidly at low cost is important to protecting the health and safety of humans and animals and the security of food chains. MSU researchers have developed novel gold (Au) nanoparticle...
Published: 2/17/2023
|
Inventor(s):
Evangelyn Alocilja
,
Hanna Miller
,
Michael Anderson
,
Edith Torres-Chavolla
Keywords(s):
Category(s):
Medical
,
Biotechnology
,
Food Science and Nutrition
Magnetic Nanoparticles, Magnetically Activated Cell Enrichment, and Biosensing
der-collapse: collapse; } Executive Summary Harmful microbes are present in a variety of sources including water, food, plants, environment, and through human-to-human transmission. The ability to detect them rapidly at low cost is important to protecting the health and safety of humans and animals and the security of food chains. MSU researchers...
Published: 2/17/2023
|
Inventor(s):
Evangelyn Alocilja
Keywords(s):
Category(s):
Medical
,
Biotechnology
,
Food Science and Nutrition
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