Search Results - biotechnology

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Enzymatic Route for Production of 3-Hydroxypropionic acid (3-HP)

­ Executive Summary Most organic (carbon-containing) chemicals used today are derived from petroleum or natural gas. Increasingly, companies are looking for alternative carbon sources to meet a growing demands for sustainability. 3-Hydroxypropionic acid (3-HP) is an intermediate that can be transformed into many important chemicals used in a variety...
Published: 11/15/2021   |   Inventor(s): Karen Draths, James Geiger, Amaya Sirinimal Mathes Hewage, Hadi Nayebi Gavgani
Keywords(s):   Category(s): Chemicals, Biotechnology

Recombinant Protein for Rare Earth Element Binding

Executive Summary Rare earth elements (REEs) are essential materials used in advanced technologies such as electronics, process catalysts, magnets, batteries and MRI contrast agents. Although used in small quantities for each application, they end up in surface water and soil during mining, processing and waste disposal. This presents growing environmental...
Published: 10/29/2021   |   Inventor(s): Harvey Lee, Connor Grady, Assaf Gilad
Keywords(s):   Category(s): Medical, Biotechnology, Environment, Test and Measurement

Microfluidic Apparatus For Respirometry

Executive Summary Cellular respiration is a set of metabolic processes responsible for the conversion of chemical energy in all aerobic organisms. In animal and plant cells this takes place in the mitochondria where food is broken down to CO2 and strongly reducing compounds. Energy released upon oxidation of the latter by molecular oxygen via a chain...
Published: 10/20/2021   |   Inventor(s): Denis Proshlyakov, Julia Busik
Keywords(s):   Category(s): Medical, Devices, Pharmaceutical, Test and Measurement, Biotechnology

Antibacterial Silicate Glass-Ceramic Filament for 3D Printing Bone Materials

INTRODUCTION The use of 3D printed porous scaffolds provides a multi-dimensional template that closely mimics the native structure of bone. This is beneficial for creating ideal conditions for bone tissue regeneration. Silicate bioactive glass-ceramics are inherently bioconductive and bioinductive, making them ideal for tissue regeneration. DESCRIPTION...
Published: 6/14/2021   |   Inventor(s): Aljoscha Roch NO LONGER AT MSU, Xanthippi Chatzistavrou
Keywords(s):   Category(s): Medical, Biotechnology, Pharmaceutical

Therapeutic for Tissue Healing and Resistive Bacteria

INTRODUCTION Healing infected tissue and combating resistant bacteria are significant clinical challenges. Antibiotic-based therapies are increasingly unsuccessful due to the ability of pathogens to develop resistance. Methicillin resistant Staphylococcus aureus (MRSA), for example, is a leading cause of many infections, including skin and soft tissue...
Published: 6/14/2021   |   Inventor(s): Xanthippi Chatzistavrou, Neal Hammer
Keywords(s):   Category(s): Medical, Biotechnology, Pharmaceutical

Engineered Shell Proteins to Enable Electron Transfer Across the Shell of a Bacterial Microcompartment

INTRODUCTION Bacterial microcompartments (BMCs) are organelles used by various bacteria to encapsulate metabolic pathways into a proteinaceous shell. Because of their attributes (self-assembling modules, optimization of the reactions in their lumen.) they have potential as catalytic bioreactors that can be customized to support new metabolic functions....
Published: 3/3/2021   |   Inventor(s): Cheryl Kerfeld, Clement Aussignargues
Keywords(s):   Category(s): Biotechnology, Chemicals, Energy, Environmental, Manufacturing Equipment

Viridiflorol Production

INTRODUCTION: Viridiflorol is a terpene bioproduct that has been isolated from the essential oils of a variety of plants including Melaleuca quinquenervia (broad-leaved paperbark). Terpenes make up a large class of natural plant products with applications that range from fragrances, cosmetics, to agrichemicals, insecticides and pharmaceuticals. The...

Surface TSPO in blood cells: Biomarker of peripheral and brain inflammation

INTRODUCTIONTranslocator Protein 18kDa (TSPO) is a nuclear encoded outer mitochondrial membrane protein that is ubiquitously expressed by most host cells. Initially, TSPO was a diazepam target, but it has also been referred to as an ‘orphan protein searching for a function’. Since the generation of these knockouts, TSPO has been determined...
Published: 8/10/2020   |   Inventor(s): Norbert Kaminski, Robert Crawford, Lance Blevins
Keywords(s):   Category(s): Medical, Biotechnology, Test and Measurement

Genetic Engineering of Oils In Vegetable (Non-Seed) Tissues By Diverting Carbon From Starch

INTRODUCTIONTriacylglycerol (TAG) is an ester that is derived from three fatty acids and glycerol. Triglycerides are the main constituents vegetable oil. Generally, in an oil crop species, TAG is produced in seeds, and this TAG can be harvested for various uses. TAG from plant oils are used as feedstocks for biofuels, food and industrial chemicals....
Published: 5/22/2020   |   Inventor(s): Christoph Benning, Sanjaya Sanjaya
Keywords(s):   Category(s): Biotechnology, Agriculture

Evolution Of Models To Predict Protein Function Using Genetic Programming

INTRODUCTIONGenetic Programming (GP) follows the concept put forth by Darwin – “Survival of the Fittest”. Species that evolve and adapt in response to the environment are more likely to survive. GP evolves models that can optimize peptides and proteins for variety of applications. It requires only basic understanding in protein engineering....
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