Antibacterial Silicate Glass-Ceramic Filament for 3D Printing Bone Materials

INTRODUCTION

The use of 3D printed porous scaffolds provides a multi-dimensional template that closely mimics the native structure of bone. This is beneficial for creating ideal conditions for bone tissue regeneration. Silicate bioactive glass-ceramics are inherently bioconductive and bioinductive, making them ideal for tissue regeneration.

DESCRIPTION OF TECHNOLOGY

The inventors have fabricated 3D printed silicate bioactive and antibacterial silver-doped glass-ceramic (Ag-BG) scaffolds using a fused filament fabrication (FFF) additive manufacturing technique. The thermal debinding and sintering processes minimize the structural deformation of the Ag-BG scaffolds and the compressive strength of these Ag-BG scaffolds is in the range of cancellous bone. The inventors have shown that the 3D printed scaffolds also have bioactive behavior and anti-methicillin resistant Staphylococcus aureus (MRSA) activity.

BENEFITS

  • Promotes bone tissue growth. Suitable for load bearing applications
  • Anti-MRSA activity

APPLICATIONS

  • Prosthetics and Orthopedics
  • Bone tissue engineering

PATENT STATUS

Patent pending. Published application US 2020/0330510 A1

LICENSING RIGHTS

Full licensing rights available

INVENTORS

Dr. Xanthippi Chatzistavrou, Dr. Aljoscha Roch

TECH ID

TEC2020-0106

Patent Information:

For Information, Contact:

Jon Debling
Technology Manager
Michigan State University
deblingj@msu.edu
Keywords: