MSU Technologies

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Spectroscopic Bioagent Detection

VALUE PROPOSITION The need for Identifying viruses quickly and accurately has become more apparent than ever. Each cell, virus, nanoparticle vibrates at a natural frequency. This technology is a phonon spectroscopy-based microscope that accurately identifies single nanoparticles and viruses. The device can be used for detecting single viruses or...

Published: 9/24/2024 | Inventor(s): Elad Harel

Keywords(s): Category(s): Medical, Analytical Instruments, Biotechnology, Environmental, Photonics

Therapeutic for Tissue Healing and Resistive Bacteria

INTRODUCTION Healing infected tissue and combating resistant bacteria are significant clinical challenges. Antibiotic-based therapies are increasingly unsuccessful due to the ability of pathogens to develop resistance. Methicillin resistant Staphylococcus aureus (MRSA), for example, is a leading cause of many infections, including skin and soft tissue...

Published: 8/5/2024 | Inventor(s): Xanthippi Chatzistavrou, Neal Hammer

Keywords(s): Category(s): Medical, Biotechnology, Pharmaceutical

MRI RF Powered Voltage Sensor

VALUE PROPOSITION For Magnetic Resonance Imaging it is often desirable to measure electrophysical characteristics alongside MRI data. To do so, voltage sensors are employed. This technology is an RF powered voltage sensor which can be configurable to measure a variety of physical indicators with excellent resolution. The design minimizes interference...

Published: 7/29/2024 | Inventor(s): Chunqi Qian

Keywords(s): Category(s): Medical, Test and Measurement, Biotechnology

Well-Characterized Non-Genetically Modified Bovine Muscle Cell Lines for Research Use

Well-Characterized Non-Genetically Modified Bovine Muscle Cell Lines for Research Use Executive Summary: Well-characterized non-genetically modified bovine primary muscle cell lines have been sorted based on genetic information and proliferate well for research use. Background: Animal cell lines are utilized for a variety of medical and veterinary...

Published: 5/6/2024 | Inventor(s): Jongkyoo Kim

Keywords(s): Category(s): Agricultural, Agriculture, Animal/Veterinary, Biotechnology, Veterinary, Therapeutic

Electrically Active Magnetic Nanoparticle-based Biosensors

Executive Summary Harmful microbes are present in various sources including water, food, plants, and through human-to-human transmission. The ability to detect them rapidly at a low cost is important to protecting the health and safety of humans and animals and the security of food chains. MSU researchers have developed novel nanoparticle-based biosensors...

Published: 3/29/2024 | Inventor(s): Evangelyn Alocilja, Sudeshna Pal, Emma Setterington

Keywords(s): Biosensors, Magnetic Beads, Magnetic Separation, Molecular Sample Processing, Nanoparticles, Polyaniline Category(s): Biotechnology, Test and Measurement, Devices, Electrical

A Novel Enzyme from Solanum Habrochaites that Synthesizes Sesquiterpenes

IntroductionZingiberene is a sesquiterpene produced by many plant species including ginger, turmeric, cultivated tomato, and its wild relatives. It is synthesized at particularly high levels in the trichomes of certain accessions of the wild tomato species Solanum habrochaites and is a potent insect repellent. The identification of a gene from S. habrochaites...

Published: 8/22/2023 | Inventor(s): Cornelius Barry, Eliana Gonzales-Vigil

Keywords(s): Insect Resistance, Terpene, Transgenic Crops Category(s): Biotechnology, Agriculture

Rapid Point of Care Detection of Tuberculosis

Executive Summary Tuberculosis (TB) remains one of the major causes of death from a single infectious agent worldwide, affecting both humans and livestock. Pulmonary TB can be currently diagnosed by various methods including chest radiography, sputum smear microscopy, nucleic acid amplification and cultivation of Mycobacterium tuberculosis (Mtb). However,...

Published: 10/14/2024 | Inventor(s): Evangelyn Alocilja

Keywords(s): Category(s): Medical, Biotechnology, Veterinary

Synthetic Bacterial Microcompartment Shell Proteins Derived by Circular Permutation and/or Genetic Fusion

INTRODUCTION Bacterial microcompartments (BMCs) are organelles used by various bacteria to encapsulate metabolic pathways into a proteinaceous shell. BMCs serve as scaffolds to organize encapsulated enzymes and as physical boundaries to reduce diffusive loss of volatile or toxic intermediates and restrict crosstalk with cytosolic biosynthetic pathways....

Published: 4/7/2023 | Inventor(s): Cheryl Kerfeld, Bryan Ferlez, Markus Sutter, Andrew Hagen, Nancy Sloan

Keywords(s): Category(s): Biotechnology, Energy, Chemicals, Environmental, Manufacturing Equipment

Bioluminescent Dopamine and Glutamate Sensors

Executive Summary Genetically encoded optical sensors and advancements in microscopy have revolutionized the scientific toolbox used for answering complex biological questions especially in terms of studying brain activity. However, there remains a need to develop new tools for reporting neuronal activity in vivo within deeper structures. MSU...

Published: 2/17/2023 | Inventor(s): Eric Petersen

Keywords(s): Category(s): Medical, Biotechnology

Extracellular Vesicle Library for Drug Screening

Executive Summary The body’s natural transporter, Extracellular vesicles (EVs), have gained recent attention for their potential as targeted drug delivery vehicles with low immunogenic response. Properly designing the surface allows EVs to deliver therapeutic payloads (protein, RNA, nanoparticle, small molecule, etc.) to a target organ....

Published: 10/16/2023 | Inventor(s): Christopher Contag, Masako Harada