Search Results - christopher colvin

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Inhibition of the Mycobacterium Tuberculosis Virulence Using Ethoxzolamide

Executive SummaryTo address the pitfalls of traditional antibiotic tuberculosis therapies, such as the emergence of multi-drug resistant bacterial strains, alternative treatment strategies are currently being pursued. Researchers at Michigan State University (MSU) have developed a promising anti-virulence treatment strategy for Mycobacterium tuberculosis...
Published: 12/28/2016   |   Inventor(s): Robert Abramovitch, Benjamin Johnson, Christopher Colvin
Keywords(s):   Category(s): Medical, Pharmaceutical

Chemical Compounds that Limit Mycobacterium Tuberculosis Growth in Vitro or in Vivo

Executive SummaryMycobacterium tuberculosis (M. tuberculosis) causes the disease tuberculosis (TB) in humans. Driven by the hypoxic environment of the granuloma, M. tuberculosis enters a persistent, non-replicating state that is recalcitrant to antibiotic therapy. Treatment requires a multidrug, 6-9 month therapeutic regimen which has fueled the emergence...
Published: 10/14/2016   |   Inventor(s): Robert Abramovitch, Christopher Colvin, Benjamin Johnson
Keywords(s):   Category(s): Pharmaceutical, Medical

Immortalized Chick Fibroblast Cell Line for Production of Human and Veterinary Vaccines

IntroductionCell-culture-based technology for vaccine production is robust, reliable, and could become a practical alternative for the pharmaceutical industry. Once the virus is propagated and harvested, the downstream processing parameters for purification, filling, and packaging of the vaccine are similar to current pharmaceutical methodologies and...