Search Results - Biotechnology

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Biosynthesis of Chemically Diversified Non-Natural Terpene Products

Executive SummaryDrug and chemical discovery is a lengthy, difficult, and inefficient process. The production of new drugs and chemicals is bottlenecked at synthesis or biosynthesis of complicated molecules, especially chiral molecules. Furthermore, diversification of current drug and chemical libraries is hindered by these difficult and inefficient...
Published: 1/8/2020   |   Inventor(s): Edmund Ellsworth, Matthew Giletto, Bjoern Hamberger, Garret Miller, Richard Neubig
Keywords(s):   Category(s): Biotechnology, Chemicals

Transcription factors to improve plant resistance to insects

Executive SummaryAs sessile organisms, plants must be able to adapt swiftly to biotic and environmental stimuli, and often do this through transcriptional reprogramming. Upon wounding by a ravenous insect, for instance, jasmonic acid (JA) increases in concentration within a cell and interacts with members of the JAZ family of repressor proteins. Ultimately,...
Published: 7/16/2019   |   Inventor(s): Gregg Howe, Marcelo Campos, Yuki Yoshida
Keywords(s):   Category(s): Biotechnology, Agriculture

Method for Improved Production of Terpenoids Using Co-Engineered Lipid Droplets and Anchoring of Terpene Biosynthetic Enzymes on Their Surface

Executive SummaryThis technology addresses one of the main hurdles of plant production and extraction of terpenoids by capturing desired terpenes in lipid droplets in plant cells.  The lipid droplets are readily extracted using standard processes used in the vegetable oil and biodiesel industries, and the high-value terpenes can be easily separated...
Published: 5/28/2019   |   Inventor(s): Bjoern Hamberger, Radin Sadre, Christoph Benning, Jacob Bibik
Keywords(s):   Category(s): Agriculture, Chemicals, Biotechnology, Pharmaceutical

Method for Production of Novel Diterpene Scaffolds

Executive SummaryMany insecticides currently in use are problematic due to persistence in the environment and off target effects including accumulation in apex predator species. Therefore effective crop-protecting agents that are naturally sourced and that overcome some of these side effects are under increasing demand. This technology identifies biosynthetic...
Published: 5/28/2019   |   Inventor(s): Bjoern Hamberger, Sean Johnson, Wajid Bhat
Keywords(s):   Category(s): Agriculture, Chemicals, Biotechnology, Pharmaceutical

Two Phase Consortium for Production of Metabolites from a Cyanobacteria/Bacteria Mixed Consortium

Executive SummaryBiobased plastics and chemicals offer an alternative solution to products traditionally made from fossil fuel sources. Bioindustries utilize heterotrophic organisms to convert carbohydrate-rich feedstocks like sugarcane, sugar beets, and corn into value-added compounds (e.g. nutritional supplements, pharmaceuticals, etc.). Because these...
Published: 5/28/2019   |   Inventor(s): Daniel Ducat, Taylor Weiss, Eric Young
Keywords(s):   Category(s): Biotechnology, Agricultural, Chemicals, Energy

Stabilization and Upgrading of Bio-Oil Using Electrocatalytic Hydrogenation

Executive SummaryPyrolyzing biomass into bio-oil is one option to convert biomass into a useable, easily transported form with minimal inputs. However, pyrolysis-derived bio-oil contains hundreds of reactive organic compounds that are corrosive to container materials and prone to polymerization. Therefore, it is necessary to be able to rapidly convert...
Published: 5/28/2019   |   Inventor(s): Christopher Saffron, Dennis Miller, James Jackson, Zhenglong Li
Keywords(s):   Category(s): Advanced Materials, Biotechnology

Method to Increase Algal Biomass and Enhance its Quality for the Production of Fuel

Executive SummaryBiodiesel is a popular alternative to fossil fuels. Most biodiesel is made from conversion of plant material, particularly edible plants that may otherwise be used as food sources. An excellent alternative would be algal biodiesel production. Algae can be grown on marginal lands that would not be used for food production, and are more...
Published: 5/28/2019   |   Inventor(s): Christoph Benning, Xiaobo Li, Bensheng Liu, Min-Hao Kuo, Barbara Sears
Keywords(s):   Category(s): Biotechnology

Genetically Modified Plants for Increased Cell Wall Biomass

Executive SummaryPlant secondary cell walls are the bulk of plant biomass in woody plants. They are necessary for plant growth and are important for numerous industries, including pulp and paper, timber, and biomass feedstocks. Regulating secondary cell wall synthesis in trees and other plants could speed up biomass production for these industries.Description...
Published: 5/28/2019   |   Inventor(s): Kyung-Hwan Han, Im Jong Hee
Keywords(s):   Category(s): Agricultural, Biotechnology

Pre-Treatment Method for Metals Determination in Aqueous Samples

Executive SummaryPractical detection of heavy metals in aqueous samples is a challenge for many testing and monitoring stations around the world. Heavy metal poisoning is the cause of thousands of deaths and disabilities. Specifically, metals including lead, arsenic, cadmium, and mercury have a direct impact on global health and are listed as four of...
Published: 12/10/2018   |   Inventor(s): Cory Rusinek, Michael Becker, Thomas Schuelke, Mary Ensch
Keywords(s):   Category(s): Medical, Biotechnology, Test and Measurement

020009: Compositions and Methods for Epizootic Catarrhal Enteritis (ECE) Therapeutics and Diagnostics in Ferrets

In 1999, a coronavirus was identified as the cause of Epizootic Catarrhal Enteritis (ECE) in ferrets, a highly contagious diarrheal disease for which there are no effective diagnostics, therapeutics, or preventatives. This disease costs ferret breeders and owners millions of dollars a year in health care costs and lost revenue. In 1996, approximately...
Published: 11/27/2018   |   Inventor(s): Roger Maes, Matti Kiupel, Annabel Wise
Keywords(s): Coronavirus, Diagnosis, Ferret, Prevention, Screening, Treatment, Vaccine Category(s): Biotechnology, Pharmaceutical, Animal/Veterinary
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