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New Quinoline-Based Proteasome Inhibitors

Executive Summary There are several existing cancer treatments that are effective at inducing cell death by decreasing proteasome activity: Velcade® (bortezomib) and Kyprolis® (carfilzomib). Due to undesirable side effects and pharmacodynamics properties, these agents have been limited to treating blood cancers. MSU researchers have developed...
Published: 10/1/2024   |   Inventor(s): Aaron Odom, Jetze Tepe, Teri Lansdell
Keywords(s):   Category(s): Medical