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Preparation of Hymenialdisine Derivatives and potential Application to Treatment of Inflammatory Diseases, Alzheimer's, and Cancer

IntroductionCyclin-dependent kinases and NF-kB regulate a large number of genes and biochemical pathways. Deviations in their activity are associated with diseases, including those linked to immune, inflammatory, and anti-apoptotic responses. Many areas of drug discovery are focused on discovery of reagents that inhibit their activities. Naturally occurring...
Published: 5/23/2023   |   Inventor(s): Jetze Tepe
Keywords(s): Anti-inflammatory, Hymenialdisine, Indolazepine, Kinase Inhibitors, NF-kB Inhibitors Category(s): Medical, Biotechnology, Pharmaceutical