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Efficient Room Temperature, Ambient Pressure Liquid Ammonia Storage System

Executive Summary Liquid ammonia is current stored and transported in very large quantities in refrigerated units, railcars, tanker trucks and pressurized containers. While the majority of existing uses are as a nitrogen fertilizer for agricultural uses, increasing attention has been turned to ammonia as a green, carbon free energy storage medium for...
Published: 5/17/2023   |   Inventor(s): Mi Chenija, Reza Ghazfar, Milton Smith, Iii, Thomas Hamann
Keywords(s):   Category(s): Chemicals, Agriculture, Energy, Environment, Transportation

Catalytic Processes for Boronic Esters and Substituted Boranes

Executive Summary In the pharmaceutical industry, organoboron complexes are key building blocks for drug manufacturing, versatile reagents for high-throughput parallel synthesis in drug discovery and exhibit some useful and unique biological activities. However, conventional synthesis routes can be complex and involve undesirable reagents. MSU researchers...
Published: 5/11/2023   |   Inventor(s): Milton Smith, Iii, Robert Maleczka, Ghayoor Chotana
Keywords(s):   Category(s): Chemicals, Pharmaceutical

Synthesis of Caprolactam from Lysine

Executive Summary Caprolactam is used in important polymer products such as the polyamide Nylon 6. Most Caprolactam is produced from petroleum based feedstocks and there is a desire for a more sustainable route for making the monomer. MSU researchers have developed a technology for synthesizing epsilon-caprolactam from L-lysine with yields up to 75%...
Published: 5/25/2023   |   Inventor(s): John Frost
Keywords(s):   Category(s): Chemicals, Environmental

Synthetic Bacterial Microcompartment Shell Proteins Derived by Circular Permutation and/or Genetic Fusion

INTRODUCTION Bacterial microcompartments (BMCs) are organelles used by various bacteria to encapsulate metabolic pathways into a proteinaceous shell. BMCs serve as scaffolds to organize encapsulated enzymes and as physical boundaries to reduce diffusive loss of volatile or toxic intermediates and restrict crosstalk with cytosolic biosynthetic pathways....
Published: 4/7/2023   |   Inventor(s): Cheryl Kerfeld, Bryan Ferlez, Markus Sutter, Andrew Hagen, Nancy Sloan
Keywords(s):   Category(s): Biotechnology, Energy, Chemicals, Environmental, Manufacturing Equipment

Efficient Process for Lignin Extraction

­ Executive Summary Lignin, is an abundant organic polymer found in plant cell walls such as wood and bark. Increasingly, the use of lignin is growing in various applications as researchers explore the potential of this renewable resource. However, the ability to extract the lignin from the plants in an eco friendly and efficient manner remains...
Published: 5/22/2023   |   Inventor(s): John Dorgan, Michael Eyser, Clayton Perbix
Keywords(s):   Category(s): Agricultural, Chemicals

Mechanistic Basis of Pyrethrum Repellency Against Mosquitoes

­High-Throughput Screening Platform for Identification of Insect Repellents Executive Summary: High-throughput screening platform identifies repellent compounds that activate specific insect odor receptors. This platform can identify pyrethrins and pyrethroids to combine with odorant-mediated repellents to enhance overall repellant activity....
Published: 2/17/2023   |   Inventor(s): Ke Dong, Feng Liu, Qiang Wang, Peng Xu, Felipe Andreazza, Wilson Valbon
Keywords(s):   Category(s): Medical, Chemicals, Veterinary

Convenient Synthesis of Carbazoles without Precious Metal Catalysts

­ Executive Summary Carbazoles are structures that have two benzene rings on either side of a five-membered ring that contains nitrogen. They are used in a wide variety of photochemical and electrochemical applications including pharma, biomedical, OLEDs, pigments and batteries. However, the current synthesis of carbazoles requires harsh temperatures,...
Published: 2/17/2023   |   Inventor(s): Thomas Guarr, Addison Duda, Michael Giurini
Keywords(s):   Category(s): Chemicals

Cost Efficient Process Generates a Stronger Titanium Alloy

Executive Summary Conventional Ti alloys are expensive and complex to develop, but remain coveted by the aerospace and nuclear power industries for their elevated heat properties and low density. MSU researchers have developed a new method for creating a durable, low-cost titanium alloy which is a lightweight alternative for nickel and cobalt alloys. Description...
Published: 4/7/2023   |   Inventor(s): Carl Boehlert, Vahid Khademi
Keywords(s):   Category(s): Advanced Materials, Chemicals

Naturally Derived Inhibitors of Fungal Toxin Production

­ ToxBlox: NATURE-DERIVED COMPOUNDS THAT inhibit aflatoxin AND DON CONTAMINATION iNTRODUCTION Nothing ruins a crop of corn quite like the aflatoxin produced by fungi, such as Aspergillus parasiticus. This toxin degrades the food and makes consumption dangerous, especially in children and pets. If crops are found to be contaminated with an...
Published: 2/17/2023   |   Inventor(s): Frances Trail, Arthur (Daniel) Jones, III
Keywords(s):   Category(s): Agriculture, Chemicals, Food Science and Nutrition

Lichen Compounds that Inhibit Aflatoxin Production

­ ToxBlox: NATURE-DERIVED COMPOUNDS THAT inhibit aflatoxin AND DON CONTAMINATION iNTRODUCTION Nothing ruins a crop of corn quite like the aflatoxin produced by fungi, such as Aspergillus parasiticus. This toxin degrades the food and makes consumption dangerous, especially in children and pets. If crops are found to be contaminated with an...
Published: 8/20/2022   |   Inventor(s): Frances Trail, Ludmila Roze, John Linz
Keywords(s):   Category(s): Agricultural, Chemicals, Food Science and Nutrition
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