Medicinal plant compound reduces mycotoxins and sporulation

 

Executive Summary

 

Economic losses due to mycotoxins in the United States are estimated to be between $0.5 and $1.5 billion annually. Fungicides are only partially effective against mycotoxin-producing fungi because such fungi are naturally tolerant to many fungicides, and because when stressed by fungicide applications, fungi can respond by producing more of the mycotoxin. Durable host plant resistance is not available, despite many years of intensive breeding. An alternative to these solutions would be a compound or compounds that block mycotoxin biosynthesis, especially when mycotoxin levels can be high, even in asymptomatic nuts and grains. A medicinal plant extract shows promise in safely replacing synthetic pesticides for prevention of aflatoxin contamination in stored grains and nuts Diospyros species root powder, root powder extracts, and purified DQ and 3-HDQ compounds all effectively inhibit aflatoxin production. DQ and 3-HDQ also block spore formation by Aspergillus.

 

Description Technology

 

This technology is compositions useful for blocking mycotoxin production and spore production by fungi that contaminate grains and nuts, thereby stabilizing the quality of stored grains and nuts.  This reduces post-harvest losses due to mycotoxin contamination.  The compositions may also be used to treat crop plants pre-harvest.  Compositions include Diospyros root powder, root powder extracts, and the active compounds DQ and 3-HDQ.

 

Key Benefits

  • Reduces aflatoxin accumulation
  • Natural products
  • Readily available
  • Inexpensive

Applications

  • Food crops:  storage or pre-harvest application
  • Animal feed: storage or pre-harvest application

 

Patent Status:

 

Provisional patent application filed

 

Licensing Rights Available

 

Full licensing rights available

 

Inventors: Gale M. Strasburg, Juma A. Mmongoyo, John E. Linz, Felicia Wu, Jovin K. Mugula Amila A. Dissanayake, Chuan-Rui Zhang, Josephine M. Wee, Muraleedharan G. Nair

 

Tech ID: 2017-0033

 

Patent Information:

Category(s):

For Information, Contact:

Thomas Herlache
Assistant Director
Michigan State University
herlache@msu.edu
Keywords: