Liquid Activated Textile Biosensing Platform



Executive Summary


Wearable devices have found considerable market success, in part, due to advances in affordable technology. One area of significant interest is in the area of wearable medical devices for consumers for monitoring an individual’s physiological condition. While devices for monitoring heart rate, blood oxygen, temperature exist, there remains a need for an affordable technology for monitoring other biofluids. MSU researchers have developed a new electrochemical sensor for biomolecular detection that is embroidered on a textile. The sensor is flexible, repeatable and robust with excellent selectivity. Multiple sensors can be combined for separate analysis of different biomarkers.


Description of Technology


The sensors utilize a conductive thread which is embroidered in a textile to create a three electrode system. On one of the electrodes, the thread contains an immobilized enzyme suitable for the analyte of interest. The embroidery pattern is done in an optimal manner so as to enhance signal quality. Sensors have been embroidered in a polyester fabric and commercial gauze and wound dressing. The sensors have been tested with glucose, lactate and uric acid showing linear response and very high correlation coefficients and selectivity with simultaneous analyze detection. To test durability, 90 degree and folding tests have been conducted (up to 100 cycles) with no observable change in response. 


Key Benefits

  • Light weight, and unobtrusive: user mobility and comfort are not compromised
  • Flexible, robust sensors; can withstand repeated mechanical stresses without loss of accuracy
  • Can multiplex sensors for simultaneous multiple analyze measurements
  • Can be integrated with a liquid embedded battery and wirelessly connected to a smartphone application.



  • Continuous health care monitoring
  • Early disease detection
  • Environmental monitoring


Patent Status:


Patent pending. Published application US 2019/0137436 A1 



Licensing Rights Available


Full licensing rights available.




Lab on a Chip article

Biosensors and Bioelectronics Article


Inventors: Peter Lillehoj, and Xiyuan Liu.


Tech ID: TEC2015-0112


Patent Information:

For Information, Contact:

Jon Debling
Technology Manager
Michigan State University