Exhaled Breath Analyzer for Lung Transplant Monitoring
Lung transplantation is a therapeutic option for patients suffering from the end stage of various lung diseases. Monitoring for signs of rejection is an invasive process that requires biopsies of a small portion of the lung. A new MSU technology allows for the monitoring of lung transplant rejection through biomarkers in the patient’s breath.
Description of Technology
This MSU technology is a combined sensor that detects peroxynitrite and nitric oxide levels. The patient breathes into the portable device and a multichannel potentiostat allows for the detection of these biomarkers. High levels of these species are indicative of lung transplant rejection.
- Non-invasive: enables lung transplant monitoring without invasive and expensive lung biopsies
- Combined sensor: allows for detection of both NO and peroxynitrite
- Portable: can be easily utilized in clinical setting
- Reusable: only have to change the disposable filter
- Lung transplantation: can detect early stages of acute or chronic lung transplant rejection
- Lung cancer diagnosis: excessive production of reactive oxygen species is found in lung cancer patients
Licensing Rights Available
Full licensing rights available.
Inventors: Dr. Greg Swain, Serban Peteu, and Dr. Borys Hrinczenko
Tech ID: TEC2016-0135
For Information, Contact:
Michigan State University