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Inhibition of the Mycobacterium Tuberculosis Virulence Using Ethoxzolamide
Executive SummaryTo address the pitfalls of traditional antibiotic tuberculosis therapies, such as the emergence of multi-drug resistant bacterial strains, alternative treatment strategies are currently being pursued. Researchers at Michigan State University (MSU) have developed a promising anti-virulence treatment strategy for Mycobacterium tuberculosis...
Chemical Compounds that Limit Mycobacterium Tuberculosis Growth in Vitro or in Vivo
Executive SummaryMycobacterium tuberculosis (M. tuberculosis) causes the disease tuberculosis (TB) in humans. Driven by the hypoxic environment of the granuloma, M. tuberculosis enters a persistent, non-replicating state that is recalcitrant to antibiotic therapy. Treatment requires a multidrug, 6-9 month therapeutic regimen which has fueled the emergence...
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