Search Results - christopher+waters

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Drug Combination Therapy to Eradicate Biofilm Formation

Executive SummaryBacterial biofilm formation is a major cause of morbidity and mortality in cystic fibrosis patients with pulmonary infections. The biofilm acts as a tough shield against the body’s own defense mechanisms and makes current antibiotic treatment extremely challenging, often resulting in a chronic, progressive course of the disease....
Published: 9/9/2015   |   Inventor(s): Christopher Waters, Alessandra Hunt
Keywords(s):   Category(s): Medical, Pharmaceutical

Anti-Biofilm Compound 1 (ABC-1) and Associated Derivative Molecules

IntroductionBacteria commonly attach to living and nonliving surfaces in the form of biofilms. In this morphology, the bacteria synthesize a matrix of extracellular polymeric substances (EPS) that provide the biofilm with protection and structural support. The EPS also gives the biofilm resistance to antibiotics and immune system clearance, making biofilms...
Published: 8/4/2011   |   Inventor(s): Christopher Waters, Karthik Sambanthamoorthy, Matthew Neiditch, Martin Semmelhack
Keywords(s): Biofilm, Film, Pathogen Category(s): Biotechnology