High-Speed, Wideband, and Widefield Coherent Raman Imaging

VALUE PROPOSITION
Inter- and intra-molecular interactions in solids dictate a variety of physical and chemical properties, ranging from structural characteristics and carrier transports to reaction pathways and the emergence of topological states. In heterogeneous materials, compositional changes and local nanoscale environments tune these properties spatially. Correlating molecular interactions with structural and compositional features necessitates statistical analysis across numerous measurements to establish direct causal relationships. An analysis apparatus is needed for parallel mapping of local/delocalized vibrational motion and carrier dynamics.  Applications for this technology include real-time drug screening, counterfeit identification, biological imaging, materials screening, food inspection, and many other areas where the chemical and physical properties of a target need to be mapped at high speed.  

DESCRIPTION OF TECHNOLOGY
In this invention a method to acquire wideband Raman spectra across a wide field-of-view and at high-speed is described.  Using a high-speed camera and high-speed optical delay line, a time-domain interferogram at each pixel of the camera is recorded.  Two short optical pulses are used to prepare the vibrational coherence and probe the response with femtosecond temporal resolution.  The instrument can achieve video frame rate acquisition (> 20 Hz) across a wide spectral band from the sub-terahertz region to tens of terahertz across a wide field of view (> 20 microns in the current implementation but larger with higher power laser sources).  

BENEFITS
•    Wide Field of View, >20 microns
•    High-Speed acquisition, >20 Hz
•    Wideband Raman Spectra, sub-Terahertz to tens of Terahertz 

APPLICATIONS
•    Real-time Drug Screening 
•    Counterfeit Identification 
•    Biological Imaging
•    Materials Screening
•    Food Inspection

IP STATUS
Patent Pending

LICENSING RIGHTS AVAILABLE
Full licensing rights available

DEVELOPER: Dr. Elad Harel

TECH ID: TEC2023-0054

For more information about this technology, 
contact Raymond DeVito Ph. D. at devitora@msu.edu or 1(517)884-1658
 

Patent Information:

For Information, Contact:

Raymond Devito
Technology Manager
Michigan State University
devitora@msu.edu
Inventors:
Elad Harel
Keywords: