MSU Technologies

Super-resolution Optical Imaging

VALUE PROPOSITION

Conventional microscopes rely on making a spatial measurement of light, which are diffraction limited. Traditional scanning microscopy approaches obtain a spatial image by scanning across known locations. The wavelength of light becomes the limiting factor in achieving better spatial resolution. It would be advantageous to have a system using light that was not bound by diffraction limitations.

DESCRIPTION OF TECHNOLOGY

This technology is an optical imaging apparatus that uses light emitted from a laser, where the leading phase front of the light is tilted creating a gradient of the light at a specimen to provide a spatial-temporal relationship. An image of the specimen is created by rotating the gradient light and reconstructing an image of the specimen from initial and the rotated orientation images. The technology uses a gradient reconstruction imaging method with a non-spatial measurement to allow for resolution that is not limited by diffraction. The resolution may be enhanced by more than two orders of magnitude over conventional optical imaging.

BENEFITS