Search Results - Jonathan Walton

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Cyclic Peptide Production Enzymes and System

Executive SummaryCyclic peptides tend to be resistant to peptidases and therefore stable in vivo. Their size, chemical properties, and ability to interact with biomolecules suggest that they make good pharmaceutical and agricultural active ingredient candidates. However, intra-molecular cyclization is difficult and competes with unwanted inter-mol...
Published: 6/14/2017   |   Inventor(s): Jonathan Walton, Heather Hallen-Adams, John Scott-Craig, Hong Luo
Keywords(s):   Category(s): Biotechnology, Chemicals, Pharmaceutical

Alpha-Xylosidase: A New Enzyme for Enhancing Conversion of Lignocellulosic Biomass to Fermentable Sugars

Executive SummaryProducing cellulosic ethanol from biomass feedstock such as corn stover requires the breakdown of sturdy cell wall materials, including cellulose, hemicellulose, and lignin, into fermentable sugars. This breakdown is facilitated commercially by various enzyme cocktails. However, the high cost of enzymes has been a major barrier t...
Published: 10/26/2016   |   Inventor(s): Jonathan Walton, John Scott-Craig, Melissa Borrusch
Keywords(s):   Category(s): Energy, Chemicals

Gene for Increasing Level of Methylesterified Homogalacturonan for Improving Digestibility of Plant Biomasses

IntroductionProduction of fuels and value-added chemicals from plant biomass often requires pretreatment of the biomass. Pretreatment increases the capital equipment needs and costs of the final product. Additionally, the use of seeds as a feedstock has been controversial, with some claiming that use of seeds for chemical production is increasing...

Identification of the Gene for Amatoxin and Phallatoxin

Executive SummaryAmatoxins and phallotoxins, natural products found in poisonous mushrooms, are deadly in high concentrations. However, there is increased research activity to explore possible clinical applications of these toxins and other cyclic peptides. Because cyclic peptides have not been successfully produced in large amounts in the laborato...
Published: 8/25/2011   |   Inventor(s): Jonathan Walton, Heather Hallen-Adams, John Scott-Craig, Hong Luo
Keywords(s): Actin, Amanitin, Mushroom poisoning, RNA polymerase Category(s): Biotechnology