Convenient Synthesis of Carbazoles without Precious Metal Catalysts
Case ID:
TEC2022-0027
Web Published:
4/27/2022

Executive Summary
Carbazoles are structures that have two benzene rings on either side of a five-membered ring that contains nitrogen. They are used in a wide variety of photochemical and electrochemical applications including pharma, biomedical, OLEDs, pigments and batteries. However, the current synthesis of carbazoles requires harsh temperatures, complicated ring building reactions and precious metal catalysts. MSU researchers have recently discovered a new method of synthesizing carbazoles that requires mild reaction temperatures and no precious metals leading to a straight forward, cost effective process.
Description of the Technology
This technology utilizes hypervalent iodine and diphenyl amines to synthesize carbazole compounds. No precious metals such as palladium are required leading to simpler purification of the resulting product. This technology has currently been demonstrated at laboratory scale.
Benefits
- Simple chemistry for carbazole synthesis
- Does not require precious metals
- Variety of carbazoles can be made by this process with various substituted groups on the phenyl rings
Applications
- OLEDS (solar cells, LEDS, smart phones, flat screen TV’s)
- Smart glass
- Pharmaceuticals
- Biomedical dyes
- Pigments
- Batteries
Patent Status
Patent pending
Licensing Rights
Full licensing rights available
References
SynOpen publication
Inventors
Dr. Tom Guarr, Addison Duda, Michael Giurini
TECH ID
TEC2022-0027
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For Information, Contact:
Jon Debling
Technology Manager
Michigan State University
deblingj@msu.edu