Process and Intermediate Compounds for the Preparation of Pyrrolidines
Description of Technology
Michigan State University’s invention relates to the preparation of pyrrolidines, preferably chiral, from tri-O-acetylketopentulosonic acid methyl esters. In particular, the invention relates to the preparation of 3,4-dihydroxy-5-hydroxymethyl pyrrolidines, which can be substituted or unsubstituted in the N position.
U.S. patents 6,518,437; 6,482,973; 6,482,974; 6,492,543; and 6,583,297
Japanese patent 3,394,047
For Information, Contact:
Michigan State University