Process and Intermediate Compounds for the Preparation of Pyrrolidines

 

Description of Technology

 

Michigan State University’s invention relates to the preparation of pyrrolidines, preferably chiral, from tri-O-acetylketopentulosonic acid methyl esters. In particular, the invention relates to the preparation of 3,4-dihydroxy-5-hydroxymethyl pyrrolidines, which can be substituted or unsubstituted in the N position.

 

Patent Status

 

U.S. patents 6,518,437; 6,482,973; 6,482,974; 6,492,543; and 6,583,297

Japanese patent 3,394,047

 

Inventors

 

Rawle Hollingsworth

 

Tech ID

 

TEC2000-0073

 

Patent Information:

Category(s):

For Information, Contact:

Thomas Herlache
Assistant Director
Michigan State University
herlache@msu.edu
Inventors:
Rawle Hollingsworth
Keywords: