Process for the Preparation of a 1,5-Dideoxy-1, 5-Imino Hexitols from Oximes and Imines

 

Description of Technology

 

Michigan State University’s invention relates to a multi-step synthesis of a 1, 5-dideoxy-1, 5-imino hexitol from a ketoaldonic acid methyl ester of a hexose sugar with protected hydroxyl groups to novel intermediates. In particular, the invention relates to processes which enable the production of novel intermediates to the hexitol and, in particular, a ketoaldonic acid methyl ester oxime or alkylimine, which forms the ring structure of the hexitol by alternate routes.

 

Patent Status

 

U.S. patents 6,462,197; 6,590,121; 6,605,724; and 6,831,176

 

Inventors

 

Rawle Hollingsworth, Gabriela Pistia-Brueggeman

 

Tech ID

 

TEC2000-0060

 

Patent Information:

Category(s):

For Information, Contact:

Thomas Herlache
Assistant Director
Michigan State University
herlache@msu.edu
Keywords: