Quantitative Histological Analysis Tool (QuHAnt)


Executive Summary


Digital pathology and whole slide imaging are increasingly popular for toxicological studies. However, quantitative approaches in histopathology can be onerous, time-consuming, and subject to inter- and intra-individual variability. MSU researchers have developed a high throughput tool for the quantification of histological features within whole slide tissue images. The computational quantitative assessment allows for rapid, precise, cost-effective and unbiased histopathological analysis in large studies.


Description of Technology


MSU researchers have developed a program which allows for the computational quantification of comparative histological features. The software automatically detects markers indicating disease and toxicity of the tissue and quantifies histological features that are indicative of a response to the toxin/chemical of interest (i.e. drugs, nanoparticles, viruses, bacteria, radiation).


Key Benefits

  • Fast, accurate, and high throughput
  • Reduced cost
  • Adaptable



  • High throughput histopathological analysis


Patent Status


Under review


Licensing Rights Available


Full licensing rights available


Inventors: Tim Zacharewski, Rance Nault, Colbry Dirk


Tech ID: TEC2014-0104


Patent Information:

For Information, Contact:

Brian Copple
Technology Manager
Michigan State University