Non-invasive biomedical imaging




There has been an increasing need for more effective ways in diagnosing cancer. Current, technologies are widely available for fluorescently labeling tumors; however, UV and visible light cannot penetrate living tissue. In addition, during a surgery there is a need for ensuring that the entire tumor has been removed with clean margins and that no tumor remnants have been left behind. Thus, there is a need for illuminating the tumors in a way that they become apparent even when they are covered by layers of tissue.


Description of Technology


Michigan State University has developed a non-invasive biomedical imaging source that can be used for diagnosis before and during surgery. The methods in this technology use much simpler optics than those prescribed in two-photon imaging as well as methods included in the use of UV light, which can cause DNA damage and does not penetrate beyond a few layers of cells.


Key Benefits

  • Detect Cancer: localizes the cancer location within a 1 mm3.
  • Determines bone density
  • Performs optical mammography 



  • Cancer diagnosis
  • Brain/cancer surgery – Robotic arm held system that positions the instrument without risk of touching the tissue


Patent Status


Patent pending




Marcos Dantus


Tech ID




Patent Information:


For Information, Contact:

Raymond Devito
Technology Manager
Michigan State University
Marcos Dantus