Search Results - hong luo

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Cyclic Peptide Production Enzymes and System

Executive SummaryCyclic peptides tend to be resistant to peptidases and therefore stable in vivo. Their size, chemical properties, and ability to interact with biomolecules suggest that they make good pharmaceutical and agricultural active ingredient candidates. However, intra-molecular cyclization is difficult and competes with unwanted inter-mol...
Published: 6/14/2017   |   Inventor(s): Jonathan Walton, Heather Hallen-Adams, John Scott-Craig, Hong Luo
Keywords(s):   Category(s): Biotechnology, Chemicals, Pharmaceutical

Identification of the Gene for Amatoxin and Phallatoxin

Executive SummaryAmatoxins and phallotoxins, natural products found in poisonous mushrooms, are deadly in high concentrations. However, there is increased research activity to explore possible clinical applications of these toxins and other cyclic peptides. Because cyclic peptides have not been successfully produced in large amounts in the laborato...
Published: 8/25/2011   |   Inventor(s): Jonathan Walton, Heather Hallen-Adams, John Scott-Craig, Hong Luo
Keywords(s): Actin, Amanitin, Mushroom poisoning, RNA polymerase Category(s): Biotechnology