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Enhancement of Proteasome Activity for the Treatment of Neurodegenerative Diseases

Executive SummaryAs we age, a decrease in the 20S proteasome’s activity level yields an increase in the accumulation and aggregation of toxic proteins, which are the classical hallmarks of neurodegenerative diseases such as Alzheimer’s, Parkinson’s, and Huntington’s disease. Artificial activation of the proteasome leads to an...
Published: 12/4/2017   |   Inventor(s): Jetze Tepe, Theresa Lansdell, Evert Njomen, Corey Jones
Keywords(s):   Category(s): Biotechnology