Search Results - claire vieille

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Improved Technology for Mannitol Production

Executive SummaryIndustrialized production of mannitol for use as a food sweetener and various pharmaceutical applications is currently achieved by hydrogenation of a fructose/glucose syrup at high pressures and temperatures. The reaction produces a mixture of mannitol and sorbitol that is both inefficient (70% sorbitol as end-product) and requires...
Published: 5/31/2018   |   Inventor(s): Claire Vieille, Seung Hoon Song, J. Gregory Zeikus
Keywords(s):   Category(s): Chemicals, Biotechnology, Pharmaceutical

Molecular Design of Thermostable Alcohol Dehydroganase for Synthesis for Chiral Aromatic Alcohols

IntroductionChiral aromatic alcohols are important building blocks for a variety of high-value chemicals, including pharmaceuticals, agrochemicals, and various other chiral compounds. Generally only one enantiomer is biologically active for the intended purpose of the drug; the other enantiomer can be toxic. To achieve enantiomeric purity using current...
Published: 8/31/2011   |   Inventor(s): J. Gregory Zeikus, Karla Fjeld, Claire Vieille
Keywords(s): Chiral alcohols, Enzyme thermostable Category(s): Biotechnology, Chemicals