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Oct4, Sox2, Klf4, and cMyc Induced Extraembryonic Endoderm Stem (iXEN) Cells in Parallel to iPS Cells

IntroductionIn recent years the multipotent extraembryonic endoderm (XEN) stem cells have been a focus of intense research. In Vivo, XEN cells contribute to the formation of the extraembryonic endoderm, visceral and parietal endoderm and later on, the yolk sac. The mature mouse blastocyst consists of three distinct cell types: the trophectoderm, which...
Published: 5/12/2016   |   Inventor(s): Amy Ralston
Keywords(s):   Category(s): Biotechnology, Medical